Document Details
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Document Type |
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Thesis |
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Document Title |
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Prevalence and Relationship of Helicobacter Pylori in Clinical Isolates with Blood group and serum Electrolytes تفشي وعلاقة هيليكوباكتر بيلوري في عزلات سريرية مع مجموعات الدم والكتروليتات المصل |
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Subject |
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Faculty of Science |
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Document Language |
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Arabic |
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Abstract |
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Helicobacter pylori are the microaerophilic bacteria that grow in digestive tract of humans and can attack the stomach lining. It infects almost half of world population and in some cases it can lead to ulcer and gastritis and if not treated Cancer. As on date this is the first time such study is carried out for Saudi patients, representing the relationship between the ABO blood group and the H. pylori infection. In our study different ABO blood group system was analysed. 33% of the patients were from O+, with no significant different between male and female group. 38% were from A+, male 15 % the percentage of female was almost 40% higher than males 23%. 5% males were B+, and females were double the male patients 10%. AB+ group almost showed the same trend but the female patients were only 3%. The RH-, ABO blood group patients were only 6%. The maximum patient 3% were from O- in male category and no one from female category. The results of total 100 subjects demonstrate that 42 % of males and 52% of female were Rh+ taking the tally to 94%. Only 6% were Rh- with 4% male and 2% female. Sodium a primary cation ions play important role in extra cellular fluids in human, helps in transport of nutrients and waste from body. In 32% patient’s sodium was below the normal range and in 25% it was above the normal range. Hyponatremia in 32% of patient is a big value, particularly from the patients of A+, B+ and O+ where the value is almost double for A+ patients. The normal potassium serum levels are between approximately is 3.5 to 5.5 mEq/L. In our study. 2% patients were in normal range of various ABO blood group. In 98% patient potassium was above the normal range and none was below the normal range. All the A+ patients (38%), except one 32% of O+ , all B+ (15%), and AB+ (8%) were have potassium level above the normal range. 93% of ABO RH positive have high potassium level and only 5% were RH negative. Magnesium is an intracellular cations and act as a cofactor for more than 900 enzymes, with its involvement in DNA transcription, DNA structure maintenance, regulation of cell proliferation, differentiation, apoptosis and bone metabolism. Our study clearly demonstrate the elevated level of magnesium in all patients, 38% patients were from A+ blood group, 33%from O+, 15%,8%, from B and AB+ respectively . 3%, 1%, 2% were from O-, B- and AB- respectively. The results of this study clearly indicates the patients with blood group O+ and A+ irrespective of sex are at higher risk of H. pylori infection. Hence more safety is required for the universal blood group O+ donor in high endemic areas. Similar precaution needs to take in case of B+ blood group population. Interestingly Rh- is the least affected population in this study of ABO blood group with minimum risk. |
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Supervisor |
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Prof.Fahad A. Al-Abbasi |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1442 AH
2020 AD |
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Co-Supervisor |
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Prof.Firoz Anwar |
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Added Date |
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Tuesday, November 3, 2020 |
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Researchers
| بندر هاشم الغامدي | Alghamdi, Bandar Hashim | Researcher | Master | |
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