Faculty of Science and Arts - Khulais | Researches | A physiological study on the effects of dexamphetamine sulphate on the levels of certain amino acids and the activity of some related enzymes in the brain tissue of albino rats. 1990.

Faculty of Science and Arts - Khulais

Document Details

Document Type	:	Article In Journal
Document Title	:	A physiological study on the effects of dexamphetamine sulphate on the levels of certain amino acids and the activity of some related enzymes in the brain tissue of albino rats. 1990. درسة فسيولوجية عن تأثير عقار الديكسامفيتامين سلفات علي مستوي بعض الاحماض الامينية ونشاط بعض الانزيمات التي لها علاقة بها في نسيج مخ الفأر الابيض
Subject	:	Effect of dexaamphetamine on amino acids neurotransmitters
Document Language	:	English
Abstract	:	The effect of dexamhetamine sulphate as a CNS stimulant drug on the levels of some excitatory and inhibitort amino acids on brain tissue of albino rat was studied.The study also includes the determination of the activity of some enzymes (GOT and GPT) and the total protein content of brain tissue. It was found that the daily injection of dexamphetamine sulphate at a dose level of 0.175 mg/100 g body weight produced a marked increase in the concentration of brain glutamine, aspartic acid, asparagine, GABA, glycine, alanine and taurine at most of the tested periods, however, glutamic acid fluctuated between insignificant decrease and increase. After stopping the injection, a general decrease in the concentration of all the studied amino acids was recorded The present data also showed that there was a more highly insignificant decrease in the activity of brain GOT and more highly significant increase of GPT activity which continued even after stopping the injection It was also found that dexamphetamine sulphate caused a more highly insignificant decrease in the brain total protein content during and after stopping the injection
ISSN	:	1110-6344
Journal Name	:	proc.Egypt.Acad.Sci.
Volume	:	18
Issue Number	:	18
Publishing Year	:	1410 AH 1990 AD
Article Type	:	Article
Added Date	:	Monday, January 3, 2011

Researchers

Researcher Name (Arabic)	Researcher Name (English)	Researcher Type	Dr Grade	Email
سيد محمد راوي	Rawi, sayed mohamed	Investigator	Doctorate	rawisayed@yahoo.com

Files

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