Document Details

Document Type : Article In Journal 
Document Title :
Effect of dielderin injection on the level of certain amino acids and some enzymes in rat brain
تأئير الحقن بالديلدرين علي مستويات بعض الاحماض الامينية وعض الانزيمات في الجرذان
 
Subject : Effect of dieldrin exposure on the central nervous system 
Document Language : Arabic 
Abstract : Comp. Biochem. Physiol., 85: 437-442. Abstract: The present investigation revealed the effect of the organochlorine insecticide dieldrin at the dose level 0.25 LD50 at different time intervals on the concentration of rat brain amino acids and the activities of glutamic oxyacetic transaminase (GOT), glutamic pyruvic transaminase (GPT) and cholinesterase. The study was also extended to include the total protein content during the tested periods. The daily injection of dieldrin caused a marked decrease in the levels of glutamic acid, glutamine and taurine and an increase in the levels of aspartic acid, asparagine, GABA, glycine, lysine, serine, alanine and histidine.However, the maximal increase and decrease were recorded for most of the tested amino acids at the end of the tested period. The activity of the transaminases increased significantly. The recorded values of GOT were usually higher than GPT. Cholinesterase activity was inhibited thoroughly during all the experimental periods Total protein content was decreased in the experiment; the minimal value was given 3 days after the injection 
ISSN : 0306-4492 
Journal Name : Comp. Biochem. Physiol. 
Volume : 84 
Issue Number : 2 
Publishing Year : 1407 AH
1986 AD 
Article Type : Article 
Added Date : Monday, December 27, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سيد محمد راويRawi, sayed mohamedInvestigatorDoctoraterawisayed@yahoo.com

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