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Document Type |
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Thesis |
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Document Title |
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Regioselectivety of 1,3-cycloaddition on each of cummarin and chromone ألاختيارية الموضعية في تفاعلات الإضافة الحلقية 1 و 3 على كل من الكيومارين والكرومون |
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Subject |
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Master Thesis in Organic Chemistry |
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Document Language |
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Arabic |
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Abstract |
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The cycloaddn. of diphenylnitrilimine with coumarin and chromone gave the cycloadducts I and II, resp. The structures of these products were based on elemental and spectral analyses and alternate synthesis. The cycloaddn. of PhCCl:NNHPh (I) to a series of coumarins in C6H6 and Et3N gave benzopyrano[4,3-c]pyrazoles II (R = H, Ac, Bz, EtO2C, R1 = H; R = H, R1 = 7-OMe, 8-Me). In EtONa-EtOH, the reaction between coumarin and I afforded no cycloadducts, but yielded o(EtO2CCH:CH)C6H4OCPh:NNHPh. The Et3N-catalyzed dehydrochlorination kinetics of EtO2CCCl:NNHR (I; R = 3- or 4-Me, -Cl, -NO2, 4-CO2Et or -Ac, H), detd. in 4:1 (vol./vol.) dioxane-H2O at 30, were pseudo 1st order in Et3N. The overall 2nd order rate consts. had an LFER with - 0.533 which is consistent with a mechanism involving a fast reversible deprotonation step, leading to the conjugate base of I, followed by rate-detg. loss of Cl-. The - for each of these steps were estd. |
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Supervisor |
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Prof. Ahmed Same Abdulshakor |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1405 AH
1995 AD |
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Number Of Pages |
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203 |
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Co-Supervisor |
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Bahgat Altawell |
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Added Date |
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Monday, May 30, 2016 |
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Researchers
| احمد سامي عبدالشكور | Abdulshakor, Ahmed Same | Investigator | Doctorate | halbar@kau.edu.sa |
| بهجت الطويل | Altawell, Bahjate | Researcher | Doctorate | halbar@kau.edu.sa |
| حسن عبدالقادر البار | Albar, Hassan Abdulkader | Researcher | Master | halbar@kau.edu.sa |
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Files
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39147.pdf
| pdf | مستخلص رسالة الماجستير |
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