Document Details

Document Type : Article In Journal 
Document Title :
Current Management Strategies in Breast Cancer by Targeting Key Altered Molecular Players
Current Management Strategies in Breast Cancer by Targeting Key Altered Molecular Players
 
Document Language : English 
Abstract : Breast cancer is the second largest disease affecting women worldwide. It remains the most frequently reported and leading cause of death among women in both developed and developing countries. Tamoxifen and raloxifene are commonly used selective estrogen receptor modulators for treatment of breast cancer in women with high risk, although resistance occurs by tamoxifen after 5 years of therapy and both drugs cause uterine cancer and thromboembolic events. Aromatase inhibitors (AIs) are one of the optional modes used for breast cancer treatment. The combination of AIs along with tamoxifen can also be beneficial. Various therapeutic agents from different sources are being studied, which further need to be improved for potential outcome. For this, clinical trials based on large number of patients with optimal dose and lesser side effects have to be more in practice. Despite the clinical trials going on, there is need of better molecular models, which can identify high risk population, new agents with better benefit having less side effects, and improved biomarkers for treating breast cancer. 
ISSN : 2234-943X 
Journal Name : Front Oncol 
Volume : 6 
Issue Number : 1 
Publishing Year : 1437 AH
2016 AD 
Article Type : Article 
Added Date : Monday, May 2, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
Shazia AliAli, Shazia Investigator  
Neelima MondalMondal, Neelima Researcher  
Hani ChoudhryChoudhry, Hani Researcher  
Mahmood RasoolRasool, Mahmood Researcher  
Peter N. PushparajPushparaj, Peter N.Researcher  
Mohammad A. KhanKhan, Mohammad A.Researcher  
Maryam MahfoozMahfooz, Maryam Researcher  
Ghufrana A. SamiSami, Ghufrana A.Researcher  
Jummanah JarullahJarullah, Jummanah Researcher  
Ashraf AliAli, Ashraf Researcher  
Mohammad S. JamalJamal, Mohammad S.Researcher  

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