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Document Type |
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Article In Journal |
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Document Title |
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Residue analysis and antiacetyl cholinesterase properties of profenofos and dimethoate متبقيات البروفينوفوس والدايمثويت وتاثيرها كمثبطات لانزيم الاستيل كولين استيريز |
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Document Language |
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English |
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Abstract |
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Residue analysis and antiacetyl cholinesterase properties of profenofos and dimethoate
Abstract: Profenofos and dimethoate at half, equal and twice recommended rate were applied onto cucumber plants. The residues were determined using gas chromatograph equipped with flame photometric detection. The residue levels of profenofos on cucumber fruits at harvesting time were 0.54, 1.32, and 1.90 mg/kg for half, equal, and twice recommended rate, respectively. The corresponding values of dimethoate were 1.13, 3.85, and 4.60 mg/kg, respectively. Profenofos and dimethoate showed inhibitory effects on rat brain AchE activity with I50 values equal to 16 and 370 µM, respectively. The predicted Ki values for profenofos and dimethoate are 1.4 X 103 and 0.06 X 103 M-1 min-1,respectively. The twice-recommended field rate of dimethoate and profenofos caused 54.1 and 36.4 as a percent inhibition of control in vivo of rat brain AchE, respectively. However, profenofos was more potent inhibitor than dimethoate In vitro. |
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ISSN |
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2090-3626 |
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Journal Name |
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Mansoura University Journal of Agricultural Sciences |
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Volume |
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27 |
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Issue Number |
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9 |
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Publishing Year |
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1423 AH
2002 AD |
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Article Type |
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Article |
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Added Date |
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Monday, August 22, 2011 |
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Researchers
| محمد حمد شيبوب | Shiboob, Mohamed Hamad | Investigator | Doctorate | mshiboob2010@hotmail.com |
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