تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Preliminary Study in diagnosis and early prediction of Preeclampsia by Using FTIR Spectroscopy Technique
Preliminary Study in diagnosis and early prediction of Preeclampsia by Using FTIR Spectroscopy Technique
 
الموضوع : كيمياء حيوية 
لغة الوثيقة : الانجليزية 
المستخلص : Background: Preeclampsia is a heterogeneous condition, potentially involving several separate pathophysiological pathways; currently no clinical screening test is useful for prediction of preeclampsia development. Fourier-transform infrared spectroscopy (FT-IR) holds great promise for clinical chemistry measurements. Methods: FT-IR spectra of serum samples from pregnant women -14 patients and 31 normotensive were obtained. Absorbance ratios, second derivative spectra, ANOVA test and personal correlation statistical analysis were tacking in comparison studies. The parameters studied were proteins and lipids. Results: Different absorbance ratios for specific bands were calculated and plotted versus the patient samples. These ratios yielded statistically significant increase/decrease among the groups under investigation. The results showed that among the normotensive control group three subjects later developed preeclampsia. The results obtained from the IR-measured (amide A/amide B) ratio of serum confirmed, with 92.9 % confidence level, the effectiveness of this technique for the diagnosis of preeclampsia. Normotensive pregnant women who developed preeclampsia were considered as subjects at high risk. Conclusion: This study suggests, for the first time that FT-IR spectroscopy can be successfully used as an accurate and rapid test, for diagnosis and early prediction of preeclampsia, starting from 20 week of gestation. 
ردمد : 1097-8135 
اسم الدورية : Life Science Journal 
المجلد : 8 
العدد : 2 
سنة النشر : 1432 هـ
2011 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Monday, December 26, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
جيهان عبدالرؤوفA. Raouf, Gehan باحثدكتوراهgehan_raouf@hotmail.com
عبدالرحمن لبيد المالكيAl-Malki, Abdulrahman Lباحثدكتوراهalalmalki@kau.edu.sa
نسمه منصوريMansouri, Nesma باحثدكتوراهnmansouri@kau.edu.sa
رقية محمد المحموديAl-Mahmoudi, Rogaia Mباحثماجستير 

الملفات

اسم الملفالنوعالوصف
 31782.pdf pdfAbstract

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