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نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Malignant eccrine poroma
Malignant eccrine poroma
 
لغة الوثيقة : الانجليزية 
المستخلص : Benign eccrine poroma arises from the intraepidermal portion of the eccrine gland duct. Malignant transformation is rare and should be suspected when these lesions present with pain, bleeding or itching. We report a 44-year-old male patient who presented primarily with a lesion diagnostic of benign eccrine poroma of the right foot sole with no clear evidence of malignancy, which was incompletely excised, followed 5 months later by local recurrence, ulceration, occasional bleeding and right inguina11ymphadenopathy. Incomplete excision of the primary tumor as well as excision of a skin lesion on the right knee joint revealed malignant eccrine poroma with aggressive histology, lymphovascular and perineural invasion. Investigations revealed no evidence of distant metastasis. This tumor might be malignant at the first presentation, which was not confirmed histopathologically considering the short duration of only 5 months for malignant transformation. The patient received 3 cycles of Docetaxel (Taxotere), Cisplatin combination chemotherapy with partial response. The management of metastatic malignant eccrine poroma is difficult. It has proven resistant to many chemotherapeutic agents and radiotherapy. 
ردمد : 1110-5607 
اسم الدورية : Saudi Med J 
المجلد : 26 
العدد : 5 
سنة النشر : 1426 هـ
2005 م
 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Saturday, January 15, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
محمود الاحولAI-Ahwal, Mahmoud باحثدكتوراه 

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 28621.doc doc 

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