تفاصيل الوثيقة نوع الوثيقة : مقال في مجلة دورية  عنوان الوثيقة : The use of chloral hydrate in pediatric electroencephalography The use of chloral hydrate in pediatric electroencephalography   لغة الوثيقة : الانجليزية  المستخلص : Objective: Sleep is a known activator of epileptiform discharges on electroencephalography. Chloral hydrate is used frequently for electroencephalography sedation. Our objectives were to study the value and limitations of chloral hydrate. Methods: One hundred and fifty nine consecutive pediatric electroencephalograms were included prospectively. One electroencephalography technologist collected chloral hydrate related data. Electroencephalogram requisitions and recordings were reviewed separately by one certified electroencephalographer. Results: The children’s ages ranged between 8 days to 19 years (mean=5.7 years). Natural sleep was recorded in 11% and only 2% were sleep deprived. Sedation was given to 45% mostly using chloral hydrate (96%). Children with chronic neurological abnormalities were more likely to receive chloral hydrate (odds ratio=9.8, 95% confidence The use of chloral hydrate in pediatric electroencephalography Mohammed M.S. Jan, MBChB, FRCP (C), Marilou F. Aquino, EEG Tech. From the Department of Neurosciences (Jan), King Faisal Specialist Hospital and Research Center and The Neurophysiology Unit (Aquino), King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia. Received 29th August 2000. Accepted for publication in final form 12th December 2000. Address correspondence and reprint request to: Dr Mohammed M.S. Jan, Department of Neurosciences, King Faisal Specialist Hospital & Research Center, MCB J-76, PO Box 40047, Jeddah 21499, Kingdom of Saudi Arabia. Tel. 00 966 2 667 7777 Ext 5819. Fax. 00966 2 667 7777 Ext 5813. interval=4.5-21). Chloral hydrate was effective in inducing sleep in 97%, however, 34% of the children woke up spontaneously before the test was completed, particularly those with chronic neurological abnormalities (p=0.0003). A second dose was necessary in 13%. Recording an initial period of wakefulness followed by sleep onset was more likely achieved in natural sleep electroencephalograms when compared to the sedated group (82% vs 10%, p<0.0001). These electroencephalograms were more likely to contain epileptiform discharges (p<0.001). Conclusion: Although chloral hydrate was effective in sleep induction, the sleep onset was frequently missed and the hypnotic effects were not sustained, particularly in children with chronic neurological abnormalities.  ردمد : 1658-3183  اسم الدورية : Neurosciences  المجلد : 6  العدد : 2  سنة النشر : 1422 هـ 2001 م  نوع المقالة : مقالة علمية  تاريخ الاضافة على الموقع : Sunday, April 20, 2008  الباحثون اسم الباحث (عربي) اسم الباحث (انجليزي) نوع الباحث المرتبة العلمية البريد الالكتروني محمد جان Jan, Mohammed باحث رئيسي دكتوراه   الملفات اسم الملف النوع الوصف  Chloral.pdf pdf مشاهدة المقالة العلمية كاملة الرجوع إلى صفحة الأبحاث